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Core Technology
Panlabs is dedicated to utilizing its expertise to offer customized services that help global enterprises enhance the value of microbial applications and optimize industrial production efficiency.
Strain Improvement
With over 50 years of experience in industrial microbial strain and enzyme improvement, Panlabs is highly skilled in operating various aerobic and anaerobic microorganisms. By employing professional, customized techniques combined with media optimization, we significantly increase the industrial production value of strains.
In addition to large-scale shaker fermentation selection equipment, Panlabs has integrated micro-fermentation equipment and automated systems to accelerate strain screening, improve throughput and screening efficiency, and provide our customers with the highest quality strain solutions.
Enzyme Improvement
In the field of enzyme improvement, Panlabs develops highly efficient enzymes using advanced molecular biotechnology and protein engineering to enhance catalytic reaction efficiency. Production under mild conditions not only reduces energy consumption and waste emissions but also satisfies the demands for green production, helping customers achieve their sustainable development goals.
Service Options Provided
Panlabs focuses on solving common technical challenges in the fermentation and manufacturing processes. Through innovative technologies and professional services, we enhance production efficiency and optimize processes, including:
Increase strain productivity and yield
Reduce by-product ratio
Enhance strain stability
Lower fermentation solution viscosity
Improve culture medium utilization and reduce costs
Shorten production time
Example 1
COMBINATION OF STRAIN IMPROVEMENT AND MEDIA DEVELOPMENT
(Terpenoid/Polyketide Derivative, Fungi)
Example 2
RATIONAL SELECTION OF RIBOSOME ENGINEERING
(Cyclic Polypeptide, G(-) Bacteria)
Hit rate:
Antibiotic resistance selection (ribosome engineering): 43% (3/7)
Random selection: 5.8% (4/69)
Example 3
YIELD IMPROVEMENT OF A FUNGAL ENZYME
Example 4
STRAIN IMPROVEMENT BY COMBINING GENETIC ENGINEERING AND CLASSICAL MUTATION
Combing heterologous gene expression with molecular and classical yield improvement, we optimized lactoferrin production.
For our client Agennix, Inc. (Houston, TX, USA) (Bio/Technology, 1995,13:498-503)
